Severe Hyponatremia and Hypopituitarism

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منابع مشابه

Severe hyponatremia as a frequent revealing sign of hypopituitarism after 60 years of age.

Hyponatremia is a common electrolyte disorder often attributed to the syndrome of inappropriate antidiuretic hormone secretion (SIADH) (1). This syndrome is characterized by hyponatremia secondary to increased total body water resulting from impaired renal freewater excretion. Despite their hypo-osmolality, patients with SIADH fail to suppress arginine vasopressin (AVP) secretion even when plas...

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Severe hyponatremia due to hypopituitarism with adrenal insufficiency: report on 28 cases.

OBJECTIVE Severe hyponatremia due to hypopituitarism and adrenal insufficiency can be life-threatening, and treatment with glucocorticoids is very effective once the diagnosis of the underlying disorder has been made. In our experience, the diagnosis of hypopituitarism in hyponatremic patients is often overlooked. METHODS In a retrospective study we screened the files of 185 patients with sev...

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Terlipressin Induced Severe Hyponatremia.

Terlipressin is a vasopressin analogue used for its vasoconstrictor effect in the treatment of variceal bleeding. Despite its good safety profile compared to vasopressin, some adverse reactions may occur during its use - e.g. hyponatremia. We describe a case of a cirrhotic patient with active variceal bleeding treated during two separate hospitalizations with terlipressin. In both drug treatmen...

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Bilateral carotid aneurysms unmasked by severe hypopituitarism.

We describe a patient who initially presented with severe hyponatraemia and grand mal seizures, without any focal neurological symptoms. The final diagnosis was that of giant bilateral carotid aneurysms extending into the sella turcica with anterior hypopituitarism. To the best of our knowledge, this is the first case report of symmetrical carotid aneurysms manifested exclusively by an acute en...

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Severe Hyponatremia Due to Valproic Acid Toxicity

Hyponatremia is a very commonly encountered clinical entity with potentially dangerous effects and for which many precipitating factors have been identified. We present a case of valproic acid (VPA) overdose causing profound hyponatremia, with one of the lowest serum sodium levels ever documented in literature. A 54-year-old woman with hypothyroidism, hypertension and bipolar disorder presented...

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ژورنال

عنوان ژورنال: Nephron

سال: 1995

ISSN: 1660-8151,2235-3186

DOI: 10.1159/000188574